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CBD Basics

Will CBD Make You Tired?

March 28th, 2022 by Brandy Palmer

Will CBD Make You Tired?

Does CBD Make You Sleepy?

Quick Summary

Will CBD make you tired is a popular question here in the US, simply because most of us do not get the quality sleep that we need. There are CBD products that are specifically formulated to help with sleep. However, CBD is not a sedative. Studies have shown that CBD has been shown to help individuals stay asleep, but will not generally make people sleepy.  Sleep specific CBD products often contain other ingredients like melatonin, chamomile, or the cannabinoid CBN to assist with falling asleep.

Nearly 30% of all Americans suffer from some type of sleep disruption. Whether you have full-blown insomnia or simply struggle getting to sleep sometimes, you may have considered a range of options to treat your sleep issues. Unfortunately, many common treatments for sleep problems can have a sedative effect, leaving you groggy and drowsy the next day.  We often get the question – is CBD one of those? Can CBD make you tired?

CBD is associated with getting a better night of sleep. Its sleep-promoting effects are likely due to its ability to relieve underlying conditions that cause sleep disruptions, like chronic pain and anxiety. CBD has very few side effects, and because it isn’t a sedative, it won’t make you tired during the day. In fact, studies have shown that some cannabinoids, like the raw form of CBD – CBDa – may actually make you more alert. With that said, there is no one size fits all.

Whether you are considering CBD to help you sleep better or to help alleviate symptoms of another issue, you don’t have to worry that taking CBD will make you drowsy. While the science on CBD is still emerging, it shows remarkable promise in a number of areas — and shouldn’t make you feel tired. If CBD is making you sleepy, it could be an indicator that you’ve taken more than your body can process and you may want to reduce your daily serving size.

What Is CBD?

Cannabidiol — more commonly referred to as CBD — is one of the primary cannabinoids that is found in the cannabis plant. Cannabinoids are naturally occurring compounds that interact with the endocannabinoid system (ECS). The ECS is responsible for helping our bodies maintain stability or balance (known as homeostasis).

Research on CBD and the ECS is still developing. Scientists have speculated that CBD may bind to receptors within the ECS, or that it may boost the presence of endocannabinoids in people who have a deficiency. Whatever the underlying mechanism of action may be, preliminary research has demonstrated that CBD has the potential to boost health and wellness in a number of ways.  But is sleep one of them?

Can CBD Help Me Sleep?

CBD is used to help provide a balanced endocannabinoid system (ECS) may be useful in helping to combat insomnia, a sleep disorder that may make it hard to fall asleep, stay asleep, or both. Insomnia has a number of potential causes.

CBD may help with sleep by addressing the root cause of sleeplessness more than the sleep itself. For example, preliminary research suggests that CBD can help with anxiety and sleep issues. A 2019 study of 72 adults with anxiety and/or poor sleep found that the majority of patients experienced relief from both problems within the first month of taking CBD. Importantly, the study’s authors found that CBD has very few side effects, particularly in comparison to psychiatric drugs that are commonly used to address anxiety and sleep issues.

CBD is not a sedative. Instead, it may help people who struggle with sleep by providing relief for the issue that is causing their insomnia.  There are a number of CBD products on the market that are specifically targeted for sleep.  They will contain ingredients other than CBD to make you sleepy such as melatonin and chamomile.  Melatonin is not the best fit for everyone and many people are finding CBN to be an alternative.  What is CBN? CBN is one of the more than 100 minor cannabinoids found in the hemp plant.  They’re called “minor” because they occur in lower quantities. While CBD does not make you sleepy, but rather may help you stay asleep and wake feeling more well rested, CBN may make you sleepy. So, does CBD make you tired? Not generally, but other cannabinoids may.

Will CBD Make Me Tired During the Day?

Although taking CBD may help you fall asleep and stay asleep, when answering if CBD will make you tired during the day, it won’t cause grogginess during daytime hours. That is because — unlike many prescription and over-the-counter medications — CBD does not produce a sedative effect. Instead, it appears to interact with the ECS to reduce the symptoms of physical and mental health conditions (like anxiety) that are known to interfere with sleep.

More significantly, CBD and CBDa may actually promote wakefulness. According to a 2019 review, CBD may actually help to manage sleepiness. The authors found that CBD may increase alertness and may have therapeutic use for sleep disorders that cause excessive daytime sleepiness.

In 2017, researchers from the University of Pennsylvania found that low doses of CBD can have a stimulating effect, while higher doses can help individuals have a higher quality of sleep. When a person gets “better” sleep, they are less likely to be drowsy during the day.

Importantly, there is a significant difference between THC and CBD when it comes to both sleep and drowsiness. While THC may improve sleep during the short-term, it can have a sedative effect, leading to grogginess and drowsiness during the day.

In contrast, CBD shouldn’t make you tired during the day — and may even make you more alert. By allowing you to get a full night of high-quality sleep, you are less likely to be drowsy during the day when you take CBD. You may also find that you are more wakeful when taking CBD.

Could CBD Make Me Sleepy the Day After Taking It?

Some sleep aids, like melatonin, can leave you feeling groggy the next day.  Some even describe it as a melatonin “hangover” making it difficult to concentrate.  Luckily, that is not a concern with CBD – a CBD hangover isn’t a thing. CBD in your endocannabinoid system works to balance your body, aiding in that rhythm of being tired and being awake and energetic.

Considering CBD? We’re Here to Help.

If you’re one of the millions of Americans who struggle with sleep, CBD and other cannabinoids like CBN might help you get a good night of sleep by easing symptoms of the condition(s) that are interfering with your rest. Taking CBD won’t make you tired during the day. In low amounts, CBD may actually make you more alert.

Green Wellness Life offers a full range of high quality CBD products, each of which has been independently tested. We aren’t healthcare professionals and cannot diagnose or treat any medical condition, but we can offer you the latest research on the science of CBD. Be sure to consult with your doctor before adding CBD or any supplement to your routine.

If you’re interested in learning more about CBD, our CBD 101 is a great place to start. Rather talk to a real human? We’re happy to answer your questions via telephone, (888) 772-7875, or by email at support@greenwellnesslife.com.


CBD 101 A Beginner’s Guide To CBD

March 12th, 2022 by Lashonda Broom


CBD 101 Blog

Cannabis Nurse Medical Reviewer, Lashonda Broom


Cannabinoids, or compounds found in hemp and marijuana plants, are definitely a popular topic these days.  So what’s all the fuss about? What are these compounds and how do they work? How do I take them and how much do I take? And most importantly, what will it help me with? 

Whew, that’s a lot of questions. Let’s start with our bodies and the system that these compounds interact with. It is often assumed that the benefits derived from CBD and other cannabinoids are a result of introducing some substance not already found in the body to your system. This couldn’t be farther from the truth. Let’s talk it through. 

What is CBD?

Before diving into how cannabinoids interact with the body, it’s first important to have an understanding of what CBD is. CBD is a natural essential oil that is rich in nutrients and one of over 100 different cannabinoids found in cannabis plants. Scientists are still researching cannabinoids and there may be more we haven’t yet identified. 

CBD can be found in all of the different types of cannabis plants, but it is more prominent in hemp plants where it makes up about 40% of the cannabinoids extracted from the plant. CBD is not psychoactive like THC, so it will not produce any kind of high. 

What is the ECS…Endocannabinoid System?

The Endocannabinoid System or “ECS,” is a system that provides the body with many similar cannabinoids to those of hemp oil. Cannabinoids are complex chemical compounds that act on receptors in cells. The hemp plant produces over 100 different cannabinoids (or phytocannabinoids); the human body (as well as other mammals) also naturally produces cannabinoids (or endocannabinoids). This means that your body already uses cannabinoids for many of its functions, such as regulating mood, appetite, pain-sensation, and memory. These cannabinoids promote homeostasis (balance) at every level of biological life. 

What do Cannabinoids do?

The function of cannabinoids in your body (regardless of whether they are naturally produced by your body or from a plant) is to act as receptors for cells. What these receptors do is act as conduits for messages from the brain to the cells. They are the “bridge” that enables your body to operate as it should. Because of this, they are essential for a healthy body, which includes memory, appetite, and mood.

While your body uses the endocannabinoids produced internally, it also reacts to phytocannabinoids from sources like cannabis and hemp. This is where CBD and other plant-based cannabinoid oils come in.

Endocannabinoid Receptors CB1 and CB2

The ECS is composed of two primary endocannabinoid receptors: CB1 (found predominantly in the brain, nervous system, and outlying organs and tissues) and CB2 (found predominantly in white blood cells, tonsils and spleen). Although CBD has low affinity for either of these receptors, it does interact with other nominal receptors with remarkable effects. For example, CBD activates the receptor GPR55, which has been shown to assist in treating pain and inflammation. CBD has also been shown as a partial agonist (which is a term referring to something that attaches to a cell receptor and causes an action to occur in that cell) to the 5-HT1A receptor, which may lead to cannabidiol’s anti-depressant, anti-anxiety, and neuro-protective effects.

Why take daily CBD?

Because the ECS is involved in the body’s communication with its cells and their functions (including repairs), cannabinoids are crucial for the body’s constant repair of cells and their functions – maintaining that balance. When more cannabinoids are introduced to this delicate system, they can stimulate the cells into functioning as the brain directs them to, and can facilitate healing where the body’s own ECS has failed. In this, it is clear that when the ECS is failing to do its job, phytocannabinoids from CBD oils can “pick up the slack” and act as receptors for cells that were malfunctioning due to a lack of endocannabinoids. This makes CBD crucial for maintaining (or, in many cases, restoring) a healthy balance of receptors in the body.

Isolate, Full Spectrum or Raw?

Finding the right CBD for your needs and body can be confusing. We answer customer questions all day long and we have found that there is no one size fits all. Each individual is different. So let’s take a look at the different forms of CBD: What is the difference between them? Who would use which version, and why?

Is CBD all that I want from the plant?

First of all, it’s important to understand that cannabidiol (CBD) is only one of the major compounds that are present in the cannabis plant – both hemp and marijuana. It happens to be one of the most studied compounds by scientists because of its powerful potential and the fact that it occurs in greater quantities in the plant than some of the other more than 80+ compounds. As evidence of its interest to scientists and researchers, CBD has been used in multiple pharmaceutical solutions. One of the most recent to be approved by the FDA is Epidiolex, a CBD-based drug used to treat childhood epilepsy.

Full Spectrum CBD Oil: A Rainbow of Compounds

Despite its fame, CBD is not the only major compound found in cannabis sativa. There are a range of other compounds that make up the plant. When we are talking about all of those compounds together, we use the term “full spectrum.” This is just another way to say “whole plant”. A full spectrum CBD oil means that manufacturers use the whole plant and all the cannabinoids that are naturally occurring as active ingredients in your product. 

Full-spectrum is unique in that it can introduce the user to the possible positive effects of the other components of cannabis working together, often referred to as the “entourage effect”. Though there are many different cannabinoids in the plant, here are a few of the better-known ones included in full spectrum products.

  • THC (Tetrahydrocannabinol) – Full-spectrum CBD from the hemp plant does include trace amounts of THC, which is well-known as the psychoactive element of cannabis – or the part that makes you high. That THC level can’t be more a .3% concentration when coming from a hemp plant, so it has no psychoactive effect. There is technology that is isolating the THC out of some full spectrum products making it what is now being referred to as a “broad spectrum.” This means that it started as a full spectrum (whole plant) product, but the THC was isolated and removed. These products will usually specify 0 THC.
  •  CBN (Cannabinol) – This component of cannabis does not occur in as great a quantity, so we don’t know quite enough about it yet. What science is finding is exciting, though. Some early studies are showing that there may be real benefits for people struggling with sleep issues.
  • CBG (Cannabigerol) – Interestingly, CBG has been shown to stimulate growth of new brain cells and bone growth. These unusual properties make it a fascinating compound for researchers to study.
  • THCV (Tetrahydrocannabivarin) – THCV has a similar molecular structure to THC and is also psychoactive. Research is finding that it’s very similar to CBD as well, in working to balance and neutralize cells.

All of these compounds, and many more, interact in a full-spectrum product. Who would this form of CBD work for? A full-spectrum CBD oil would work great for someone who wants to work with all the elements of the cannabis plant for a holistic approach. It would be very useful for those who are interested in other compounds, like CBG and THCV, and their effects. We have often seen excellent results for people living with inflammatory pain. 

It’s important to keep in mind that unless clearly stated to be a 0% THC product, full spectrum products will likely contain a trace amount of THC. That legal limit, if coming from hemp, is 0.3%.  While it’s not likely that quantity would cause you to fail a THC drug test, it is possible. 

CBD Isolate

In a product made with a CBD Isolate, only one cannabis compound is present – CBD. It’s been individually extracted from the plant without any of the other cannabinoids, terpenes, or plant matter. Some might say that the isolate is missing some of the other compounds that make full-spectrum oil special. While this is true to an extent, there are plenty of reasons why someone might want just the CBD oil.

For one, maybe they’re only interested in specific CBD oil impact. If a customer has discovered that CBD works best alone to treat their particular disorder or ease their symptoms, then they would definitely want to stick with what works. Other people might feel uncomfortable with even trace amounts of THC. In this case, an isolate CBD is a perfect solution. 

Others may actually be allergic or have had bad reactions to other cannabinoids or plant matter. In this case, a CBD isolate would be the best choice.  Additionally, we have seen excellent results with isolate CBD for people looking for help with mood stabilization.  The other cannabinoids and plant matter aren’t usually as necessary to see a benefit there. 


Cannabidiolic acid (CBDA) is a chemical compound found in the resin glands (trichomes) of raw cannabis plants.” In this case, raw means unheated and uncured. Many of the conditions that respond with CBD also respond well to CBDA. There is a growing body of information that is talking about the benefits of raw or CBDA having a greater effect on people living with chronic pain. There is also a patent pending by GW Pharmaceuticals using CBDA in conjunction with CBD for anxiety and psychotic disorders.

Product Options

Now that you understand the way that the ECS works and the different processing types of products that come from cannabis plants, let’s talk about products. In short, CBD and it’s fellow compounds can come in pretty much any package type that you’re interested in – from chocolate to bath bombs to hemp flower. 

Pricing will vary but will be based on total milligrams of active ingredients per container.  When you see a 300mg lotion, that means that there are 300mg of cannabinoids in that whole bottle – not in each amount that you put on your skin.  You’ll see the same thing on a tincture, bottle of gummies, etc.  Those package sizes can vary as well.  Some are much more concentrated than others, so you may have the same amount of cannabinoids (your active ingredient) and a similar price point in a tiny 10ml bottle and a large 2oz bottle.  When you’re product shopping, you will want to look at that total strength per package as well as how much you’re going to take every day. 

We break it down into three main product categories – let’s talk them through: 

1) Topicals

These cover anything that you’re applying to your skin.  

  • Benefits in 15-30 minutes.  
  • The downside is that it won’t last as long – usually 4-6 hours.  
  • Topicals are a great fit when you’re dealing with a skin issue or are looking for inflammation relief at that site.  
  • Topicals won’t generally get into your bloodstream (with the exception of some CBD patch molecules that are small enough to do so).  
  • Intended to provide relief to the muscle, joint, and skin tissue.  
  • You can definitely use a topical along with a booster and a daily supplement. 
  • Use them where it hurts – when it hurts. Consistency isn’t key here.  

2) Boosters

Boosters avoid the digestive system to get to work quickly. 

  • Benefits in 15-30 minutes.
  • Like a topical, they get to work and then dissipate within 4-6 hours.  
  • Absorbed through your cheek or taken in through your lungs.  
  • The intent is to provide a bit of extra CBD on a day when you need it.
  • Use them as needed – consistency isn’t critical.  
  • As they are quick to leave your system, we wouldn’t recommend a booster as your only source of CBD and other cannabinoids. 

3) Daily Supplements

If you’re only going to take one type of cannabinoid, we would ask that you make it a daily supplement.  You’ll ingest these – and they come in all kinds of forms: 

Raw Oil

This is the plant extract in its most natural form – it’s likely been filtered 1 or more times and will taste grassy and earthy. Your serving size will be measured in paste quantity. We use the term “grains of rice.” Raw Oils will always be Full Spectrum. 

  • Pros: No additives, Flexible Serving Size
  • Cons: Difficult to Measure/Take, Earthy Flavor


This is a liquid that you place under your tongue. It starts with the raw oil, but has a carrier oil and possibly flavoring added to it. Serving size will be measured in drops or dropperfulls. Tinctures can be Full Spectrum, Broad Spectrum or Isolated CBD. 

  • Pros: Flexible Serving Size, Added Flavoring, Quick Sublingual Absorption 
  • Cons: Can be Difficult to keep Serving Size Consistent


Capsules and Softgels are encapsulated tincture.  Serving size will be measured in capsules. 

  • Pros: Consistent Serving Size
  • Cons: Lack of Flexibility in Serving Size

Edibles (Gummies, Candies or Chocolate)

These options take a raw oil or an isolated CBD powder and add it into a gummy, candy or chocolate recipe. Raw Oils taste earthy, so full spectrum edibles are harder to come by than more filtered options. Serving size would be measured per piece. 

  • Pros: Easy to take
  • Cons: Lack of Flexibility in Serving Size, Priciest Option

How Much Do I Take?

Our goal is always to see the best possible results with a minimal amount of stuff in your system.  We talk in terms of serving size rather than “dose” because CBD is considered a food supplement – not a drug. In our experience, most people see benefit between 15-50mg daily.  We do have customers that do well with 5mg daily, and others who need 100mg, but 15-50mg taken consistently is the standard. 

We know that when you’re hurting, it’s always tempting to take a high serving to feel better.  We encourage you to step away from that and start small.  Some people do very well with a small amount of CBD to get their body back into neutral. We all want to be that person! Start there and work up if you need to. CBD supplements are intended to work over time – not instantly.  Don’t jump your serving up on a bad day – that’s what boosters are for.  If you’re not consistent in your serving size, you may not see the benefits that you are hoping for.

Getting Started

If you’re new to CBD, here’s how we recommend getting started: 

  • Day 1-5: Start with 10-15mg daily
    • Be consistent with the time of day that you take it. Raw CBD can be energizing, so we recommend morning. 
    • Any supplements that are sleep aids should be taken 30-60 minutes before bed. 
    • We always encourage you to take CBD on a full stomach.
  • Day 6-10: If you aren’t seeing the benefits you’re looking for, double your daily serving to 20-30 mg. 
    • Stay consistent
  • Day 11+: As long as you are seeing some benefit, stay the course. 
    • You can continue to increase your serving as needed, giving your body a couple days to adjust
    • You’ve got cannabinoids in your system, so your adjustment time will be quicker
    • If you’re not sure if you are seeing benefits, stop taking it for 3-5 days. That’s enough time for you to see if there was a difference for your system. 

We love starting with a tincture (liquid) because that serving size is so flexible, but if you’re more comfortable with a gummy or a softgel, go with that! The best CBD for you is the one that you will take every day. I’ll say it again: The best CBD for you is the one that you will take every day

No One Size Fits All

Whatever your choice when it comes to CBD, it’s important to make sure you’re aware of your options, in both product type and serving size. What your body needs may change. Every system is unique. We know it’s hard to hear, but there truly is no one size fits all. At the end of the day, the best CBD for you is the one that you are most comfortable with and see the greatest benefit from. 



What is CBN?

March 12th, 2022 by Hannah Laing

CBN CBD for Sleep

What is CBN?

There is a lot of talk about CBD, but there are a lot of other compounds that are equally as beneficial but rarely discussed. One of our absolute favorite compounds in the office, for a plethora of reasons, is a compound called CBN. While each of us in the office utilize products with this compound in our homes on a daily basis, you may not know what CBN is or how to properly utilize the benefits. If you struggle with sleep, falling asleep or staying asleep, boy oh boy, do I have some exciting information for you.

CBN Compound Explanation

If you think like me (which you may not – feel free to skip this section and go right to the potential benefits) but I need to know the science behind what I am putting in my body. Whether it be a pharmaceutical prescribed by a doctor and a supplement you’re trying on your own, I highly encourage taking the time to understand how those chemicals work in your body. It is an ongoing joke here at Green Wellness that I google everything in the world – CBN being no different.

CBN stands for Cannabinol, and was the first of the cannabis compounds to be isolated from a red oil extract at the end of the 19th century. From then on, our understanding of this cannabinoid has only grown. Originally CBN was understood to be formed from THC through a degradation process via light, heat, or carboxylation. THC over time and throughs tress will turn into CBN, but typically in small amounts on the vine. While CBN comes from THC, there is not the same level of intoxicating effect. CBN is significantly less potent than THC as an psychotropic agent, but there are still immense benefits that can be gained from this little compound.

Benefits of CBN

CBN is associated with drowsiness, though there is no direct evidence that exists that CBN improves sleep in humans. Nonetheless, there is a plethora of anecdotal evidence that a higher level of CBN can make us drowsy, though not every body is the same. If you have some reservations, just ask Cara about her experience with taking the Entourage softgels in the morning. She thought the drowsiness was a placebo. When she fell asleep at her desk, I will admit that I did make fun of her. CBN has not been shown to help you stay asleep though, like CBD does, so she was able to be woken up for the rest of the work day.

When I take a high CBN isolate and add it to a CBD product, I don’t find that it makes me groggy like traditional sleeping pharmaceuticals, but more like melatonin, I just become sleepy. When I was taking melatonin in the past, I found that the efficacy wore off over time and that if I wasn’t able to fall asleep upon the initial drowsiness, the drowsiness would wear off and I was left restless. With CBN, I find that the CBN continues to make me sleepy for a few hours or until I finally fall asleep, but I wake up feeling rested and not fighting to open my eyes.

CBN Recommendations

Because it’s CBD that’s been shown to help you stay asleep and CBN may help you fall asleep, our favorite products to help us on restless nights marry the two. The product that I always reach for on my bedside table is the WYLD elderberry sleep gummies that have 25mgs of CBD and 5mg of CBN. I find that that is just the right amount of CBN to make me sleepy and the perfect amount of CBD to help me stay asleep and keep my mind from racing. My sleep struggles stem from my brain’s inability to rest, often leaving me thinking about every social interaction I’ve ever had instead of sleeping like I very much need to.

Cara on the other hand, is a right and proper insomniac and she swears by the much stronger Entourage Deep Sleep Microcaps. Each little softgel has 20mgs of CBD, 20mgs of CBN, and 4mgs of CBDV. For those who are in need of a little more sleep support, the 20mgs of CBN is the highest potency that we carry and may really help.

Share Your CBN Stories

There is still so much to study when it comes to the endocannabinoid system and CBN’s role. However, it’s clear that one may be able to find some much needed sleep with a combination of both CBD and CBN. We still need to conduct more research of the effects of CBN in the body, so we would love to hear about your experiences with CBN. Please feel free to share your stories, positive or negative, on our social media and we’re always here to help! You can find us on Instagram or Facebook, or email us  at support@greenwellnesslife.com or by phone at 616-275-1039 (toll free 888-772-7875). I hope you sleep well!


Water Soluble vs Oil Soluble: What’s The Difference?

March 2nd, 2022 by Brandy Palmer

Water Soluble vs Oil Soluble : What’s the Difference?

Hemp is a sticky subject for a lot of reasons. The fact that it’s an oil is simply the most obvious one. (Not what you were thinking? “Stick” with me anyway…) We’ll cover everything you need to know about water soluble hemp oil. 

Solubility, by definition, is the ability to be dissolved, especially in water. It’s easy to understand water and oil solubility through the lens of everyday multivitamins. Many of us take multiple vitamins every day – vitamins C and E are two that are included in my daily routine. Vitamin C is water soluble while E is fat soluble. The difference is important because it determines how the vitamins are going to act in your body.

Vitamin C, or any water soluble supplement, is absorbed quickly and easily into your body. Because our bodies are approximately 60% water, we can take in those nutrients and use them fully.

Vitamin E, or anything fat soluble, will travel through the lymphatic system and be processed by the small intestine. They are stored in your body for a longer period of time, but may not be fully absorbed and quickly processed.

Traditional hemp oil supplements are just that – an oil. That makes them fat soluble. Slower to get to work, but will bind and hold in our systems. That’s a good thing, but sometimes we need a result more quickly. 

Scientists have also been able to modify hemp compounds to make them water soluble. There are now two different categories of CBD products to choose from: oil soluble and water soluble. You may have heard the two terms thrown around or you may have seen the terms while shopping for CBD. We refer to water soluble hemp oil as a “booster.” It will get to work quickly as fast acting CBD, but then dissipate more quickly as well. It’s a quick “boost” of CBD to get you through. 

Understanding Bioavailability 

To understand the primary difference between water soluble and oil soluble CBD, you need to first understand the concept of bioavailability. Bioavailability refers to the portion of a substance that is able to be absorbed by the body into the bloodstream. In other words, bioavailability is the amount of a substance that is able to have an active effect in your body. Bioavailability is important, because you will see a higher effect when your body is able to absorb more of a compound into the bloodstream. Increasing the bioavailability of CBD gives you more bang for your buck – greater benefits with less CBD. 

Bioavailability applies to compounds found in cannabis, but this effect isn’t exclusive to cannabis. Reduction in bioavailability is a common problem for many plant-based compounds, including morphine, lidocaine, curcumin, and nitroglycerin. So, now that you understand bioavailability, how does that all tie in to the difference between water soluble CBD vs oil? 

What Is Oil Soluble CBD? 

Traditionally, hemp oil supplements were all oil soluble. Cannabidiol is an oil by nature (as the name implies). As you likely already know, oil and water do not mix well. For oil to dissolve into water, it would have to break some of the hydrogen bonds in water, which doesn’t happen. Therefore, getting the body to absorb oil soluble CBD poses a challenge. CBD oil naturally resists absorption into the bloodstream to a degree. 

Bioavailability is typically the lowest when CBD is consumed orally. Certain studies have found that consumption of certain oil soluble CBD capsules result in absorption rates of only 20-30% in some cases. Of course, there are formulations that improve bioavailability. 

CBD tinctures allow individuals to place drops under the tongue for absorption (this method is believed to provide the fastest absorption). CBD lotions and creams can also be directly rubbed into the skin to directly enter systemic circulation. These oil soluble CBD products have much higher absorption rates. Nevertheless, scientists have been pushing to find ways to make CBD more water soluble, which is where water soluble CBD comes into play. 

What Is Water Soluble CBD?

The term “water soluble CBD” is technically a misnomer. Water soluble CBD doesn’t actually dissolve in water. Instead, the process of creating water soluble CBD involves breaking CBD molecules into nanoparticles and emulsifying them with a hydrophilic (water-friendly) carrier to remain stable in tiny form. As nanoparticles, the CBD molecules are then tiny enough to allow for better absorption. The tiny particles can disperse throughout water, which increases the surface area of the compound. 

So, water soluble CBD is really more water compatible CBD rather than water soluble. There are several different methods for making CBD more water friendly. The most common methods include: 

  • Nanoemulsion: Considered to be the best method for creating water soluble CBD, this process involves breaking up cannabis extract to 10-100 nanometer droplets. 
  • Microemulsion: Microemulsion involves dissolving CBD oil in water to create 100-5,000 nanometer droplets. This process requires a large amount of additives to be successful, which can create undesirable side effects. For this reason, microemulsion is not commonly utilized in the CBD industry. 
  • Liposomes: Liposomes are structures with a (water friendly) core and outer shell. CBD extract is then stored in the membrane between the core and outer shell. 

Water soluble CBD oil is more rapidly absorbed by the body and takes less time to become active when compared to oil-based counterparts. Water soluble CBD is produced in both liquid and powder forms. It can be used in capsules, topicals, edibles, tinctures, and drinks. 

Which Should You Take? 

You’ve got options when determining the best way for you to get the calming and balancing effects of hemp oil into your daily supplement regimen. If a product contains water soluble CBD, it will normally say so somewhere on the product label, like our Hemplucid Water Soluble tinctures

How you get your CBD is entirely a matter of personal preference. Traditional oil-based hemp will take longer to get to work, but will bind to your lipids and keep working for you. Water soluble options will likely allow for a much quicker effect, but that benefit will be a shorter time frame. Many people find best results when combining the two – a consistent daily oil supplement and and a water soluble CBD oil for an as needed “booster.” 

If you’re looking to try or buy CBD, you can browse our wide selection of CBD products in our shop. If you’re unsure what kind of CBD product may be best for you, our CBD 101 Beginner’s Guide is a great place to start. If you’d rather chat with a real live person, reach out. That’s what we are here for! You can reach us at support@greenwellnesslife.com or by phone at 888-772-7875. 

As always, our goal at Green Wellness Life is first to educate. We encourage you to do your own research into hemp and how it can help you live a healthier, happier life. Thanks for reading!






Does CBD Make You Hungry?

February 22nd, 2022 by Brandy Palmer

Does CBD Make You Hungry

Does CBD Make You Hungry?

If you’re considering CBD while also trying to lose weight, you may be concerned that CBD will make you eat more. We’re far from the first to tackle this question. Does CBD induce hunger? The governmental research body, PubMed, asked it way back in 2009 with this article.  Cannabis is widely known for its appetite-boosting properties. Many people don’t realize that the plant family is comprised of hundreds of compounds, and not all of them are capable of giving you ‘the munchies’.

Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most widely-studied compounds of the cannabis plant. While THC is known for its psychoactive effects, it is equally well-known for its ability to trigger hunger. Because CBD and THC are both popular cannabinoids, the two can sometimes be conflated.

How Does Cannabis Cause Increased Appetite?

The two primary plants in the cannabis family are hemp and marijuana.  Contrary to what many believe, they are not the same plant.  Once of the differences is the amount of THC and CBD found in them.  Marijuana contains more THC, while hemp contains more CBD.  THC is directly responsible for stimulating appetite in the human body. It does so by binding and interacting with the CB1 receptors in the endocannabinoid system. In contrast to CB2 receptors (which are mostly found in the peripheral organs), CB1 receptors are concentrated in the brain and central nervous system.

The CB1 receptors play a large role in regulating hunger and appetite. In fact, they can be found in areas of the brain that influence the way we feel and perceive food. These areas include the hypothalamus and basal ganglia. The hypothalamus regulates appetite and controls the onset of sensations like hunger and thirst. The basal ganglia is the reward system of the brain and it creates the sensation of pleasure derived from eating.

In addition to interacting with CB1 receptors, THC also stimulates the production of a hormone known as ghrelin. Ghrelin is a hunger hormone that is released when the stomach is empty. When ghrelin is produced when the stomach isn’t empty, you can feel hungry even when you’re not.

It is through the above interactions that THC triggers appetite when introduced into the body. Unlike THC, CBD primarily interacts with the CB2 receptors and does not interact with the CB1 receptors the same way THC does. This means that CBD won’t get you high and also won’t lead to the feeling of having the munchies.

Does CBD Impact Appetite?

Studies surrounding CBD and appetite have yielded mixed results. In a study of 117 children being treated with CBD for epilepsy, 30% of parents reported a significant increase in their child’s appetite. Additionally, a review of 2,409 people who used CBD found that 6.35% of study participants experienced increased hunger as a side effect. On the other hand, a study of 23 children with Dravet syndrome being treated with CBD found that some children experienced increases in appetite while others experienced decreases. A 2012 study by the University of Reading also observed that cannabidiol could diminish food cravings by suppressing our body’s pleasure signals.

While CBD doesn’t induce the munchies, it does still interact with the endocannabinoid system, which is responsible for balancing many important functions. If your body is out of balance the result could be an overactive or underactive appetite, in which case, CBD could help to stimulate increases or decreases in appetite.

In fact, the endocannabinoid system has been found to be largely responsible for controlling gut functions. Maintaining gut health is incredibly important for overall health and well-being. The gut communicates directly with the brain and also influences the immune system, mood level, and more. When your gut is not healthy the following conditions could arise:

  • Brain fog
  • Weight gain
  • Digestive issues like bloating and cramps
  • Constipation
  • Loose bowel movements
  • Food allergies
  • Trouble sleeping
  • Feelings of exhaustion

CB1 and CB2 receptors help regulate inflammation in the gut. The endocannabinoid system also aids in helping the gut communicate with the brain. Thus CBD could help to improve gut health, which could indirectly result in healthy weight gain or healthy weight loss if appetite was out of balance.

CBD and Weight Loss

Now that we know that CBD will not likely make you hungry, the next question is “can it help me lose weight?”  Again, the answer is a resounding “maybe.” If we circle back to the endocannabinoid system, we know that it’s all about balance.  CBD works with that system to get it back to a neutral state, which may lead to weight loss, depending on the system and the issue.  A test tube study also found that an active endocannabinoid system may lead to “brown” fat in your body, which is the fat in our bodies that burns calories.  This is preferable to “white” fat, which is the predominant fat responsible for storing energy and cushioning organs.  It’s also the type of fat most associated with chronic illness.

Summary on CBD Effects on Hunger

Unlike THC, CBD will not give you ‘the munchies’. CBD interacts with the endocannabinoid system, which helps to balance many important bodily functions, including appetite. If your body is out of balance, the result could be an overactive or underactive appetite, in which case, CBD could have an effect on appetite.

CBD may promote weight loss or gain through that system. Research is limited and more human studies are definitely needed.

Not All CBD Is Created Equal

It’s important to note that not all CBD is the same. If you’re interested in trying CBD, you’ll want to buy CBD products that are both legal and safe. Green Wellness Life was founded with the goal of being the most trusted hemp-based CBD provider on the internet. All of our products are independently tested in third party labs to ensure there are no contaminants, the CBD levels listed on the product are accurate, and the THC level is below 0.3%. All of the lab results for each of our products are available on the site.

We aren’t healthcare professionals and cannot diagnose or treat any medical condition, but we can offer you the latest research on the science of CBD. Be sure to consult with your doctor before adding CBD or any supplement to your routine.

You can use our product finder to find the product that will best suit your needs. Our staff is more than happy to assist you in your search. You can contact us by calling (888) 772-7875 or by filling out a contact form.


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